Clonorchis sinensis morphology

(Image from Atlast of parasitology) Adult Clonorchis sinensis The adult worm lives in the human biliary tract for 15 years or more. It has a flat, transparent, spatulate body; pointed anteriorly and rounded posteriorly, 10 to 25 mm long and 3 to 5 mm broad Histological and histochemical studies on Clonorchis sinensis have resulted in new information on the morphology of this species and have clarified some points in its physiology. The material for study was obtained by infecting rabbits by administration of metacercariae contained in the fresh-water fish, Pseudorasbora parva; after 6 weeks they were autopsied and the worms were collected Regarding Looss's contention that in C. sinensis the egg narrows more distinctly anteriorly and has a higher lid with a more projecting rim than that of O. endemicus, the author states that he has noticed that the exact reverse is the case. In an egg from a specimen (10 mm.) taken from a cat the shell tapered considerably anteriorly and was provided with a distinctly vaulted lid, whilst in one taken from a specimen (14 mm.) the shell tapered considerably less and was furnished with a. It is brownish in color. Unlike an adult, it has two eyespots, penetration glands and a stylet at its anterior end, and a cuticle with small spines. Metacercaria - In this form, C. sinensis is encysted and does not look like a fluke. It has lost larval organs such as the eyespots, the stylet, and the tail

Clonorchis sinensis adults are flattened, lance shaped, and measure approximately 10 to 25 mm long by 3 to 5 mm wide. The oral and ventral suckers (acetabulum) are relatively small. Like other flukes, they are hermaphroditic Clonorchis sinensis under a light microscope: Notice the uterus; this species is monoecious. An adult C. sinensis is a flattened (dorsoventrally) and leaf-shaped fluke. The body is slightly elongated and slender, measuring 15-20 mm in length and 3-4 mm in width Morphology (eggs) Small, 26-30 x 15-17 um Ovoid, yellowish color Operculated at one end, small knob at opposite end 6. Metacercariae of Clonorchis sinensis collected from digested fish. The cyst wall is elliptical 0.16-0.20 mm long. Dark granules are in the bladder. 7 Abstract. When larvae of C. sinensis reach the biliary system and mature, the flukes provoke pathological changes, both as a result of local trauma and of toxic irritation. The appearances vary with duration and severity of the infestation, but they are sufficiently distinctive and characteristic to allow a classification into four phases as.

(PDF) Clonorchis sinensis : Morphology , Life cycle and

Morphological Studies on Clonorchis sinensis

Clonorchis sinensis eggs are differentiated from those of heterophyid flukes by morphological features, such as shouldering around the operculum, wrinkles on the outer surface, and an abopercular knob. However, it is difficult to differentiate C. sinensis eggs from those of Opisthorchis spp. under a microscope. A cellophane-thick smear method (the Kato-Katz method) is widely employed in the field and the formalin-ether centrifugal sedimentation method is used with higher sensitivity and. They are 23.7-29.2 (25.7) micrometer long, 14.2-15.8 (15.4) micrometer wide, and the ratio 1.50-2.06 (1.67). From the results, it is concluded that eggs of 5 kinds of heterophyids and C. sinensis can be morphologically differentiated one another, however, careful observation and measurement on sufficient number of eggs are needed

On the Life-History and Morphology of Clonorchis sinensis

Liver Trematodes

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Morphology of Eggs of C.sinensis Eggs are small, 26-30 x 15-17 um Ovoid, yellowish color . Operculated at one end, small knob at opposite end Metacercariae of Clonorchis sinensis collected from digested fish. The cyst wall is elliptical 0.16-0.20 mm long. Dark granules are in the bladder. Fig 4: Eggs of C.sinensi The present study was undertaken to observe the morphological changes of Clonorchis sinensis obtained from experimentally infected rats treated with praziquantel (Biltricide) which is a new. The adult Chinese liver fluke, Clonorchis sinensis (Cobbold), is occupied chiefly in propagation. The average daily egg-laying capacity per fluke in a cat as the host is 2400 eggs (Faust and Khaw '26). Egg laying is continuous rather than cyclic. Since these flukes have a size range from 10 to 25 mm. in length by 3 to 5 mm. in breadth (Faust '49), the reproductive system involved in such. In order to provide some clues for differential diagnosis of trematode infections in fecal examination, the comparative morphology of eggs of 5 kinds of heterophyid flukes (Metagonimus yokogawai, Heterophyes heterophyes nocens, Heterophyopsis continua, Stellantchasmus falcatus and Pygidiopsis summa) and Clonorchis sinensis was studied Clonorchis sinensis, also known as the oriental or Chinese liver fluke, typically causes clonorchiasis. This parasite is The fluke's morphology was compatible with that of C. sinensis. The aspirated bile was stored in the test tube and was centrifuged at a speed of 3500 revolutions/min. We got the 0.5 mL bile debris a

Clonorchis sinensis, the Chinese or oriental liver fluke, is an important human parasite and is widely distributed in southern Korea, China (including Taiwan), Japan, northern Vietnam and the far eastern part of Russia. Clonorchiasis occurs in all parts of the world where there are Asian immigrants from endemic areas. The human and animal reservoir hosts (dogs, pigs, cats and rats) acquire the. Opisthorchis sinensis, O. felineus and O. viverini. Morphology These are spindloid flukes measuring about 16x4 mm. The eggs measure 29 x 16 µm. Life cycle Man is infected by eating raw or improperly cooked fish that carries the infective metacercaria in a cyst View Clonorchis_sinensis.doc from BIOL 211 at University of Massachusetts, Amherst. Clonorchis sinensis A-Classification Phylum: Platyhelminthes (flatworms) Class: Trematoda (flukes) Family Clonorchiasis is a food-borne parasitic disease caused by infection with Clonorchis sinensis (C. sinensis).Mammals are often infected with C. sinensis by consuming raw or uncooked fish or shrimp containing infectious metacercaria. Adult worms reside in the bile ducts of hosts and secreted products from C. sinensis eventually lead to clonorchiasis resulting in: cholangectasis, cholecystitis. I.H of clonorchis sinensis is this species of snail. Parafossarulus manchouricus. Geographical distribution of Clonorchis sinensis. Japan, Korea, China, Taiwan, Vietnam - Chinese liver fluke. Spreads via exported fish products with metacercaria. Morphology of C. sinensis - suckers, testes, ovaries, sex. trematode with weak suckers and muscle.

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Clonorchis sinensis - Wikipedi

Clonorchiasis sinensis - SlideShar

The morphology of the adult worms of 0. viverrini, 0. felineus and C. sinensis is similar but can be distinguished at the cercarial stage by the bilateral pattern of excretory flame cells (Vajrasthiraetal., 1961; Wykoffetal., 1965). The adults differ in the shape oftesticular lobes The proportion of pigment stone in the Clonorchis sinensis egg-positive stones was higher than in egg-negative stones (P<0.0001). In the 30 egg-positive stones examined by scanning electron microscopy, dozens or even hundreds of Clonorchis sinensis eggs were visible (×400) showing a distinct morphology. Many eggs were wrapped with surrounding. Anisakis share the common features of all nematodes: the vermiform body plan, round in cross section, and a lack of segmentation.The body cavity is reduced to a narrow pseudocoel.The mouth is located anteriorly and surrounded by projections used in feeding and sensation, with the anus slightly offset from the posterior.The squamous epithelium secretes a layered cuticle to protect the body from.

Epidemiology and prevalence of Clonorchis sinensis and Opisthorchis viverrini infection in humans. Clonorchis sinensis infection has been reported from many parts of east Asia (Russia, Japan, Korea and China), whereas O. viverrini infection has been reported from Thailand, Laos and Cambodia with prevalence reaching 100% in some endemic areas. 39-45 In Japan, clonorchiasis cases have. These structures are trematode eggs, probably Clonorchis sinensis, (Chinese liver fluke). However, the morphology of this egg closely resembles eggs within the genera Heterophyes, Metagonimus, and Opisthorchis. Note the opercular shoulders (within oval) and the small knob at the abopercula The Liver Flukes: Clonorchis sinensis, Opisthorchis spp, and Metorchis spp. 1.0 Epidemiology of the Disease and. Pathogens. Trematode parasites of the genera Clonorchis, Opisthorchis and Metorchis, commonly referred to as liver flukes, are transmitted to humans and other mammals by the ingestion of fish infected with their larval stages whic

Clonorchis sinensis: pathogenesis and clinical features of

CLONORCHIS SINENSIS Opisthorchis viverrini and Clonorchis sinensis were considered by a previous IARC Working Group in 1994 (IARC, 1994). Since that time, new data have become available, these have been incorporated in the Monograph, and taken into consideration in the present evaluation. 1. Exposure Data 1.1 Taxonomy, structure and biology 1.1. Author summary Clonorchiasis, caused by the fish-borne trematode Clonorchis sinensis, is a chronic liver infection and is classified as a neglected tropical disease, particularly in some Asian countries such as Vietnam. Light infections with C. sinensis are asymptomatic, yet heavy chronic infections are associated with clinical complications such as, bile duct obstruction, hepatic fibrosis and. Clonorchis sinensis Human liver fluke disease. Clonorchis sinensis was named after that the worm was discovered in the bile duct of a Chinese carpenter in Calcutta, a harbor city of India, in 1874. Worm block bile passage ; Clonorchiasis. Eating raw or halfcooked fresh water fish and shrimps Human liver fluke diseas The small liver fluke Clonorchis sinensis causes hepatobiliary ductal infections in humans. Clonorchiasis is characterized histopathologically by ductal dysplasia, hyperplasia and metaplasia, which closely resembles cholangiocarcinoma (CCA). The disruption of programmed cell death is critical for malignant transformation, while molecular events underlying these phenomena have poorly been.

Table 1. Measurements of the eggs of minute intestinal flukes and C. sinensis that occur in the Republic of Korea - Comparative Morphology of Minute Intestinal Fluke Eggs That Can Occur in Human Stools in the Republic of Kore General info for Clonorchis sinensis-Common name: Chinese Liver Fluke Describe the ova morphology for Clonorchis sinensis-Chinese vase-very small; ovoid; yellow-brown color-small terminal knob (abopercular)-prominent shoulders with operculum*-developing miracidia is visible Life cycle of Clonorchis sinensis-see phot Clonorchiasis is endemic in East and Southeast Asian countries. For a preventive strategy against infectious diseases, vaccination is the most effective. Here, we evaluated the molecular characteristics and immune responses of CsAg17 protein from Clonorchis sinensis, and investigated its protective effects against C. sinensis challenge. A cDNA clone encoding CsAg17 protein and containing a.

Intestinal Parasites: Comparative Morphology - Figure 9

Clonorchis sinensis Archived 2008-03-17 at the Wayback Machine. Web Atlas of Medical Pathology, accessed 1 April 2009. Kim C. H This species is medically important as a host for the liver fluke Clonorchis sinensis in East Asia. Parafossarulus manchouricus This species is a first intermediate host for Clonorchis sinensis. IUCN (2013) Clonorchis Sinensis: Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. Epidemiological investigation therefore currently relies on morphological examination of adult worms following expulsion chemotherapy. [researchrepository.murdoch.edu.au Clonorchis sinensis is a carcinogenic human liver fluke that is widespread in Asian countries. Increasing infection rates of this neglected tropical disease are leading to negative economic and public health consequences in affected regions. Experimental and epidemiological studies have shown a strong association between the incidence of cholangiocarcinoma and the infection rate of C. sinensis Clonorchiasis, caused by Clonorchis sinensis (C. sinensis) infection, is a serious food-borne zoonotic disease that is often asymptomatic or shows only mild symptoms, which leads to delayed treatment and chronic clonorchiasis and results in various complications, such as cholelithiasis, cholangitis, cholecystitis and cholangiocarcinoma. However, acute shock caused by C. sinensis infection has.

Clonorchis sinensis SpringerLin

  1. a, GN and Nguyen, HM (2017) Inter-individual and intragenomic variations in the ITS region of Clonorchis sinensis (Trematoda: Opisthorchiidae) from Russia and Vietnam. Infection, Genetics and Evolution 55, 350 - 357.CrossRef Google Scholar PubMe
  2. thes.This parasite lives in the liver of humans, and is found mainly in the common bile duct and gall bladder, feeding on bile.These animals, which are believed to be the.
  3. e and identify the different species of trematodes using prepared slides. 5. Fasciolopsis buski Morphology Ova 6. Heterophyes heterophyes 7. Metagonimus yokogawai Ova Ova

Clonorchis sinensis Heterophyes heterophyes Echinostoma ilocanum Dicrocoelium dendriticum Opistorchis felineum Metagonimus yokogawai Paragonimus westermani. Note: If humans were trematodes, they would be Dicrocoelium dendriticum because of its round, oblique testes. The longest trematode has the length of glass slide Clonorchis sinensis: 30 mm x l6 mm. Range, 27-35 mm x 11-20 mm. Small, ovoidal, or elongated with broad rounded posterior end and a convex operculum resting on shoulders. A small knob may be seen on the posterior end. Yellow brown. Embryonated. Contains mature miracidium Clonorchis sinensis: 30 mm × l6 mm. Range, 27-35 mm × 11-20 mm. Small, ovoidal, or elongated with broad rounded posterior end and a convex operculum resting on shoulders. A small knob may be seen on the posterior end. Yellow brown. Embryonated. Contains mature miracidium 1. Clonorchis sinensis ( Chinese liver fluke) 2.Schistosoma spp ( blood fluke). a. morphology description b. sex determination and size c. infective stage d. portal of entry e. diagnostic stage f. location in host g. transmission h. vector i. intermediate hosts j. lifecycle k. disease cause l. general symptoms m. geographic distribution Clonorchis sinensis and Opisthorchis species are important liver flukes of oriental or Chinese origin [1-4].Clonorchiasis whose symptoms are indistinguishable from opisthorchiasis is one of the most neglected tropical diseases which blight the lives of millions of people worldwide and threaten the health of several others [5, 6].A report by the World Health Organization in 2012 estimates a.

egg capsule with typical

Videos (0) Clonorchiasis is infection with the liver fluke Clonorchis sinensis. Infection is usually acquired by eating undercooked freshwater fish. Symptoms include fever, chills, epigastric pain, tender hepatomegaly, diarrhea, and mild jaundice. Diagnosis is by identifying eggs in the feces or duodenal contents Opisthorchis sinensis, O. felineus and O. viverini. Morphology These are spindloid flukes measuring about 16x4 mm. The eggs measure 29 x 16 µm. Life cycle Man is infected by eating raw or improperly cooked fish that carries the infective metacercaria in a cyst • The laboratory diagnosis of Clonorchis sinensis is made by examining multiple stool specimens and comparing the size and morphology of the eggs (see table). • The source of infection with liver flukes is uncooked fish or water plants Clonorchis sinensis is a human liver fluke, which is endemic in Asia, including China, Korea, and Vietnam. The incidence of C. sinensis infection is about 0.36% in China. 1 The flukes inhabit the biliary tract. Infected hosts may remain asymptomatic, possibly for decades, until complications, such as large duct biliary obstruction or cholangitis, occur Clonorchis sinensis (C. sinensis), a human liver fluke, is one of the major food-borne parasites in China [1,2]. 15-20 millions people are infected with C. sinensis and 1.52 millions show symptoms or complications mainly in China, Korea, East Russia, and Vietnam [1]. C. sinen-sis infection is thought to be a significant risk factor o

Publisher Summary Clonorchiasis commonly occurs in several countries of the Orient, including China, Japan, Korea, Taiwan and North Vietnam. The symptoms evoked in clonorchiasis fall into three categories—mild, moderate, and severe, and manifestations are progressive, depending on the period of infection, condition of the host, and possibility of hyperinfection in long-standing parasitism. Heterophyes heterophyes: Metagonimus yokogawai : Opisthorchis felineus: Opisthorchis viverrini: Clonorchis sinensis: Dicrocoelium dendriticum: Fasciola hepatic

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Morphology Morphology • Adult worm - Size & Shape like the seed of sunflower - Sucker: oral = ventral - 2 dendritic testes lie in tandem to each other in the posterior region (clonorchis) Adults of Clonorchis sinensis Clonorchis sinensis is one of the most common causes of trematodiasis that is caused by the ingestion of raw fish contaminated with infective cysts. The adult flukes are predominantly present in the intrahepatic bile ducts, but cholangiography most likely owing to the flat morphology of the organism and due to its scattered distribution Clonorchis sinensis is endemic to Southeast Asia, Japan, China, and Taiwan. Those infected often have a history of consumption of raw fresh fish. Its manifestations can be asymptomatic of cholangitis, biliary stones, or cholangiocarcinoma. A 69-year-old male living in Chishan, Taiwan visited our hospital with obstructive jaundice. Noninvasive analyses, such as stool examination, abdominal.

Video: Clonorchis sinensis egg and adult morphology (clear

Lab Exam #2 - Microbiology & Molecular Biology 417 with

tion of clonorchis sinensis in the bile duct. The majority of patients may ignore it due to the early atypical symptoms. While in the advanced stage, liver cirrhosis, cholangitis and even cholangiocarcinoma or liver cancer may be found in patients. The morphology of this parasite is hard to be foun Clonorchis sinensis b. Opisthorchis viverrini c. Fasciola hepatica d. Paragonimus westermani 3. Blood a. Schistosoma mansoni b. Schistosoma haematobium c. Schistosoma japonicum G. General adult's appearance 1. Body is non-segmented, flattened dorsal-ventrally, leaf-shaped, and covered with a cuticle which may be smooth or spiny. 2 46.5 CLONORCHIS SINENSIS 1. Introduction These are leaf shaped and flat helminthes. They are hermaphrodites. Twenty eight million people are infected worldwide. 2. Morphology a) 12-20 x 3-5 mm. in size. b) Flat, elongated, aspinous, flabby, tapering anteriorly and somewhat rounded posteriorly. c) Note: Lancet appearance The three species of flukes, Clonorchis sinensis, Opisthorchis viverrini and Opisthorchis felineus are closely related trematodes that have similar life cycles and they cause the same pathophysiology to the biliary tract. The flukes differ in their geographic distribution and morphology. The adult fluke of Clonorchis sinensis is a willow-leaflike

The voltage-gated Ca2+ channel β-subunit is a member of the membrane-associated guanylate kinase family and modulates kinetic properties of the Ca2+ channels, such as their voltage-dependent activation and inactivation rates. Two cDNA clones were identified to encode each β-subunit isotype of the voltage-gated Ca2+ channel of Clonorchis sinensis, CsCavβ1 and CsCavβ2, which consist of 606. Clonorchis sinensis.dr elvisac tratamiento, clínica, ciclo vital. Leer más usjt Seguir 4 comentarios 6 recomendaciones Estadísticas Notas Full Name. Comment goes here. 12 hours ago Delete Reply Block. Are you sure. Cathepsin D (CatD; EC family peptidases of parasitic organisms are regarded as potential drug targets as they play critical roles in the physiology and pathobiology of parasites. Previously, we characterized the biochemical features of cathepsin D isozyme 2 (CatD2) in the carcinogenic liver fluke Clonorchis sinensis (CsCatD2). In this study, we performed all-atomic molecular dynamics. clonorchis sinensis. Medical Information Search. Identification of IgE-reacting Clonorchis sinensis antigens. (1/114) Clonorchis sinensis is a liver fluke and it is the most prevalent human parasite in Korea at present

Specific and common antigens of Clonorchis sinensis and

A New PCR-Based Approach Indicates the Range of Clonorchis sinensis Now Extends to Central Thailand. PLoS Neglected Tropical Diseases, 2009. S. Leelayoova. Thomas Cribb. R. Thompson. S. Leelayoova. Thomas Cribb. R. Thompson. PDF. Download Free PDF neglected [5]. Clonorchis sinensis (C. sinensis), the orien-tal liver fluke, is endemic in parts of Asia, including China, Japan, Korea, and Vietnam. Currently, it is esti-mated that more than 200 million people are at risk of C. sinensis infection, and over 15 million are infected worldwide [6]. The parasite causes a substantial clinica Clonorchis sinensis: ( klō-nōr'kis sī-nen'sis ), The Asiatic liver fluke, a species of trematodes (family Opisthorchiidae) that in the Far East infects the bile passages of humans and other fish-eating animals; cyprinoid fish serve as chief second intermediate hosts, and various operculate snails serve as the first intermediate hosts..

Clonorchis - an overview ScienceDirect Topic

Fig. 21.4 Clonorchis sinensis eggs and Trichuris trichiura egg (upper left) in the same smear from fecal concentrate. (Courtesy of Dr. Herman Zaiman). Fig. 21.5 Clonorchis sinensis operculated eggs in an adult fluke within the bile duct. Egg morphology in tissue sections may help identify the species of fluke SECTION I-INFECTIOUS AGENT. NAME: Clonorchis sinensis SYNONYM OR CROSS REFERENCE: Clonorchiasis, Chinese or oriental liver fluke 1 Footnote 2. CHARACTERISTICS: Clonorchis sinensis is a trematode belonging to the Opisthorchiidae family Footnote 1 Footnote 3.They are macroscopic, transparent and appear 10 to 25 mm long and 3-5 mm wide, flattened or lancet shaped flukes at the mature stage. To determine the potential for immunodiagnostic application of two recombinant forms of Clonorchis sinensis omega-class glutathione transferases (rCsGSTo1 and rCsGSTo2) against human small liver-fluke C. sinensis and Opisthorchis viverrini infections 3. Video 《Clonorchis sinensis》 【instrument and equipment】 Light microscope 【requirements】 1. Study the morphology of C. sinensis, P. westermani and F. buski. 2. Study the life cycles of C. sinensis, P. westermani and F. buski.. 3 Clonorchiasis is endemic in East and Southeast Asian countries. For a preventive strategy against infectious diseases, vaccination is the most effective. Here, we evaluated the molecular characteristics and immune responses of CsAg17 protein from Clonorchis sinensis, and investigated its protective effects against C. sinensis challenge

Clonorchis sinensis - VISAVE

Clonorchis sinensis, affect the health of more than 30 million people throughout the world and are particularly prevalent in Asian countries, such as Lao PDR, Vietnam, Cambodia, Thai-land, Philippines, Taiwan, China, and Korea [1-4]. Human in-fections with FZT are almost entirely caused by the habitua morphology of eggs of heterophyids and Clonorchis sinensis causing human infections in Korea. Korean J Parasitol 22: 171-180. Lim MK, Ju YH, Franceschi S, Oh JK, Kong HJ, Hwang SS, Park SK, Cho SI, Sohn WM, Kim DI, Yoo KY, Hong ST, Shin HR (2006) Clonorchis sinensisinfection and increas-ing risk of cholangiocarcinoma in the Republic of Korea Epidemiology — C. sinensis (or Opisthorchis sinensis), also known as the Chinese liver fluke, is endemic in the Far East, particularly in China, Japan, Taiwan, Vietnam, and Korea ; it is also endemic in far eastern Russia . Clonorchis is a parasite of fish-eating mammals; dogs and cats are the most common reservoirs Comparative morphology of minute intestinal fluke eggs that can occur in human stools in the Republic of Korea Jin Joo Lee, Bong Kwang Jung, Hyemi Lim, Mi Youn Lee, Sung Yil Choi, Eun Hee Shin , Jong Yil Cha

Clonorchis sinensis - an overview ScienceDirect Topic

Jun 12, 2015 - Operculated eggs seen on stool O&P with Clonorchis sinensis. Jun 12, 2015 - Operculated eggs seen on stool O&P with Clonorchis sinensis. Pinterest. Today. Explore. When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures Introduction. Clonorchis sinensis, also known as the Chinese liver fluke, belongs to the family Opisthorchiidae, and is one of the most important foodborne parasites, endemic in Eastern Asian countries, including China, Korea, Vietnam, Thailand and the Far East regions of Russia. 1-4 Based on the most recent national survey in China in 2003, it is estimated that more than 12 million people. Production and Deformation of Clonorchis sinensis Eggs during In Vitro Maintenance Md Hafiz Uddin, Young Mee Bae , Min Ho Choi , Sung Tae Hong SNUCM Tropical Medicine and Parasitolog

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Comparative Morphology Of Eggs Of Heterophyids And

Clonorchis Sinensis is an important foodborne pathogen. It is actively transmitted in far-East countries and Asia, especially in China. It enters the biliary system via ingestion of infected cysts. It is exceedingly rare to encounter such a presentation in the Middle East, particular in Kuwait Jul 6, 2016 - The eggs of both Heterophyes heterophyes and Metagonimus yokogawai are small have an operculum and a small terminal knob opposite the operculum. The eggs are very similar in morphology to Clonorchis sinensis but can be distinguished by less distinct shoulders than Clonorchis species

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간흡충(Clonorchis sinensis)과 태국 간흡충(Opisthorchis viverrini) 간흡충(Clonorchis sinensis)은 인체 감염 시 간내 담관에 기생하여 간흡충증을 일으키는 원인으로 알려 져 있고 국내에서 감염률이 가장 높은 기생충 질환이다. 현재 전 국민의 간흡충 감염률은 2.9%이며 Clonorchis sinensis infection elicits hepatic inflammation, which can lead to cholangitis, periductal hepatic fibrosis, liver cirrhosis, and even cholangiocarcinoma. cells stimulated with C. sinensis ESPs exhibited changes in cellular morphology. During the early stages of C. sinensis infection, hepatic macrophages preferentially. CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): sinensis, are pathologically important food-borne members of the class Trematoda (Beaver et al., 1984). These flukes establish a chronic infection within the smaller.Intrahepatic bile ducts and occasionally in the pancreas and gall-bladder of humans and other fish-eating mammals Giardia lamblia cyst. Oval shape. size 7-10 x 8-12 µm. 2-4 nucleus. Axonemes or Axostyles. Space between cyst wall and content. Normal saline (Credit: Choomanee Lamom, Fac. Medical Technology, Mahidol University) Trichrome stain (Credit: Choomanee Lamom, Fac. Medical Technology, Mahidol University) Geographical distribution